Chronic active hepatitis--rare association with secondary eosinophilia.

*Assistant Professor, Sheth L.G. General Hospital, Maninagar, Ahmedabad Received: 18.11.2011; Revised: 24.07.2013; Re-revised: 19.08.2013; Accepted; 19.08.2013 Sir, H is characterised by marked increase in eosinophil count. In most cases it is reactive and found in association with parasitosis, al lergic manifestations, pulmonary inf i l t rates , mal ignancies , col lagen vascular diseases.1 It may be primary due to clonal proliferation of eosinophils. Some infrequent rare secondary causes should also be kept in mind while evaluating case of hypereosinophilia, l ike chronic active hepatit is , acute pancreatit is , chronic dialysis , post radiation and hypopituitarism.2 A 55 year old male patient, residing at Ahmedabad, was admitted in L.G. General hospital with distension of abdomen over a period of 20 days. Patient was chronic alcoholic since last 30 years. No history of previous blood transfusion, major surgery or exposure to multiple sexual partners. O n e x a m i n a t i o n , v i t a l s w e r e normal. Patient was pale. Respiratory, cardiovascular and nervous system examinations were normal. Per abdomen examination was suggestive of globular distension of abdomen with dilated veins on flanks. Liver and spleen were not palpable. A f t e r a d m i s s i o n r o u t i n e b l o o d investigations were sent. Haemoglobin was 5.8 Gm%, Total count was 51,000 cells/cumm, Neutrophil count was 36%,Lymphocyte count was 10%, Monocyte count was 01%, Eosinophil count was 53%, Basophil count was 00%. Platelet count was 1.35 lacs. Peripheral smear was suggestive of moderate hypochromia, anisocytosis, macro-ovalocyte, and eosinophilia. Random blood sugar, serum urea and serum ceatinine were within normal limits. S. bilirubin was 1.0 mg%, serum glutamic pyruvic transaminase was 60 Chronic Active Hepatitis-Rare Association with Secondary Eosinophilia